CLEARING THE JUNQ: THE MOLECULAR MACHINERY FOR SEQUESTRATION, LOCALIZATION, AND DEGRADATION OF THE JUNQ COMPARTMENT

Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

Cellular protein homeostasis (proteostasis) plays an essential role in regulating the folding, sequestration, and turnover of misfolded proteins via a network of chaperones and clearance factors.Previous work has shown that misfolded proteins are spatially sequestered into membrane-less compartments in the cell as part of the proteostasis process.S

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Analysis of immunogenicity and purification methods in conjugated polysaccharide vaccines: a new approach in fighting pathogenic bacteria

Carbohydrates are commonly found in conjunction with lipids or proteins, resulting in the formation of glycoconjugates such as glycoproteins, glycolipids, and proteoglycans.These glycoconjugates are essential in various biological activities, including inflammation, cell-cell recognition, bacterial infections, and immune response.Nonetheless, Knitw

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